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Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Magnetic resonance imaging based determination of body compartments with the versatile, interactive sparse sampling
Tania Buehler1, Nicolas Ramseier, Juergen Machann
1Department of Clinical Research, MR-Spectroscopy and Methodology, University of Bern, Bern, Switzerland.
Journal of Magnetic Resonance Imaging : JMRI
|May 31, 2012
Summary
A new Versatile, Interactive Sparse Sampling (VISS) method accurately measures visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT). VISS is reproducible and robust, offering improved accuracy for body composition analysis.
Area of Science:
- Medical Imaging
- Radiology
- Body Composition Analysis
Background:
- Radiofrequency field inhomogeneity at higher magnetic field strengths can impact volumetric measurements.
- Accurate determination of visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT) is crucial for health assessments.
Purpose of the Study:
- To address radiofrequency field inhomogeneity in volumetric MRI.
- To introduce and evaluate a Versatile, Interactive Sparse Sampling (VISS) method for VAT, SCAT, and total body volume (TBV) determination.
Main Methods:
- VISS employs contour line separation, sparse sampling, and manual correction.
- T1-weighted whole-body MRI scans from 24 subjects (12 at 1.5T, 12 at 3.0T) were analyzed.
Main Results:
- High consistency was observed for SCAT (CV 2.2%, ICC 0.993) and VAT (CV 4.9%, ICC 0.987) across raters.
- VISS showed good agreement with established methods for VAT and SCAT volumetric measurements.
- VISS demonstrated superior accuracy in estimating body weight compared to a reference method.
Conclusions:
- VISS is a reproducible and accurate method for adipose tissue and total body volume quantification.
- The VISS method is robust against artifacts common in MRI at higher field strengths.
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