Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 21, 2026

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics
12:26

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Efficient manipulation of microparticles in bubble streaming flows.

Cheng Wang1, Shreyas V Jalikop, Sascha Hilgenfeldt

  • 1Department of Mechanical Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Biomicrofluidics
|June 5, 2012
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Cullin1-based SCF E3 ubiquitin ligase targets the InR/PI3K/TOR pathway to regulate neuronal pruning.

PLoS biology·2013
Same author

Recommendations for the management of septic arthritis after ACL reconstruction.

Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA·2013
Same author

Poly(ADP-ribose) polymerase 1 promotes oxidative-stress-induced liver cell death via suppressing farnesoid X receptor α.

Molecular and cellular biology·2013
Same author

[Clinical significance of changes in T wave and ST segment amplitudes on electrocardiogram from supine to standing position among children with unexplained chest tightness or pain in resting stage].

Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics·2013
Same author

Biomimetic synthesis of equisetin and (+)-fusarisetin A.

Chemistry (Weinheim an der Bergstrasse, Germany)·2013
Same author

ERG Protein Expression Is of Limited Prognostic Value in Men with Localized Prostate Cancer.

ISRN urology·2013

Ultrasound-driven microbubbles create flows that separate microparticles by size. This microfluidic technology enables selective particle filtering, enrichment, and preconcentration based on size.

Area of Science:

  • Microfluidics
  • Acoustic manipulation
  • Particle separation

Background:

  • Oscillating microbubbles, driven by ultrasound, generate steady streaming flows.
  • Microparticles within these flows exhibit size-dependent trajectories, even when density-matched.

Purpose of the Study:

  • To investigate the size-dependent behavior of microparticles in microbubble-induced streaming flows.
  • To demonstrate the design of microfluidic devices for selective particle manipulation using these phenomena.

Main Methods:

  • Utilizing oscillating microbubbles (20-100 μm radius) driven by ultrasound.
  • Superimposing a Poiseuille flow onto the microbubble streaming flow.
  • Analyzing microparticle (1-5 μm radius) trajectories and separation characteristics.

More Related Videos

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Related Experiment Videos

Last Updated: May 21, 2026

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics
12:26

Fabrication, Operation and Flow Visualization in Surface-acoustic-wave-driven Acoustic-counterflow Microfluidics

Published on: August 27, 2013

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System
08:19

Induction of Microstreaming by Nonspherical Bubble Oscillations in an Acoustic Levitation System

Published on: May 9, 2021

Main Results:

  • Microparticle trajectories are size-dependent, allowing for separation with ~1 μm resolution.
  • Selective trapping, accumulation, and release of particles are achievable by tuning flow strengths.
  • Demonstrated designs for filtering, enriching, and preconcentrating particles of specific sizes.

Conclusions:

  • Microbubble-mediated flows offer a tunable platform for precise microparticle manipulation.
  • The developed microfluidic devices can effectively filter and concentrate particles based on size.
  • This approach provides a novel method for particle separation and preconcentration in microfluidic systems.