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Quelprud's nodule: a post-auricular cartilaginous nodule
K Khanobthamchai1, B Bingham, M Hawke
1Department of Otolaryngology, University of Toronto.
The Journal of Laryngology and Otology
|November 1, 1990
Summary
Quelprud's nodule, a small ear prominence, is common, affecting about one-third of people. This ear variation appears to be inherited in families with an autosomal dominant pattern.
Area of Science:
- Otolaryngology
- Human Genetics
Background:
- Minor variations in external ear anatomy are common.
- The posterior aspect of the pinna can present unique anatomical features.
Purpose of the Study:
- To describe a specific external ear variation, Quelprud's nodule.
- To determine the prevalence and inheritance pattern of Quelprud's nodule.
Main Methods:
- Prospective clinical survey of 208 patients at an Ear, Nose, and Throat (ENT) clinic.
- Family-based analysis to assess inheritance patterns.
Main Results:
- Quelprud's nodule, a cartilaginous prominence on the posterior pinna, was identified.
- Approximately one-third of the surveyed population exhibited Quelprud's nodule.
- An equal incidence was observed between sexes.
- Family studies suggested an autosomal dominant inheritance with variable expressivity.
Conclusions:
- Quelprud's nodule is a prevalent external ear variation.
- The condition demonstrates a likely autosomal dominant inheritance pattern with variable expressivity.