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Craniofacial variations in the tricho-dento-osseous syndrome

T Nguyen1, C Phillips, S Frazier-Bower

  • 1Department of Orthodontics, University of North Carolina, Chapel Hill, NC 27599–7450, USA. nguyent@dentistry.unc.edu

Clinical Genetics
|June 8, 2012
PubMed
Summary

Tricho-dento-osseous (TDO) syndrome, linked to the DLX3 gene, causes distinct hair, teeth, and bone issues. TDO-affected individuals exhibit a Class III skeletal pattern and specific mandibular and ramus variations compared to unaffected family members.

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