Cutaneous metastases from breast carcinoma

Area of Science:

• Oncology
• Dermatology
• Pathology

Background:

• Cutaneous metastasis from breast carcinoma is uncommon.
• Early detection and diagnosis are crucial for effective treatment.

Purpose of the Study:

• To report a rare case of cutaneous metastatic breast carcinoma.
• To describe the clinical presentation, diagnostic methods, and initial treatment.

Main Methods:

• Clinical examination, skin punch biopsy, breast ultrasound, and immunohistochemistry were performed.
• Histopathological analysis confirmed poorly differentiated grade III adenocarcinoma.

Main Results:

• The patient presented with a breast rash, supraclavicular, and axillary lymphadenopathy.
• Biopsy confirmed metastatic adenocarcinoma, estrogen receptor-negative, HER2-positive.

Conclusions:

• Cutaneous metastatic breast carcinoma can present atypically.
• HER2-positive status guides targeted therapy, such as with trastuzumab (Herceptin).