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Pulmonary functions in tropical pulmonary eosinophilia
The Indian Journal of Chest Diseases & Allied Sciences
|January 1, 1990
Summary
Tropical pulmonary eosinophilia (TPE) can cause lung function abnormalities. Treatment with diethylcarbamazine (DEC) effectively restored pulmonary function in most patients, highlighting DEC
Area of Science:
- Pulmonary Medicine
- Infectious Diseases
- Respirology
Background:
- Tropical pulmonary eosinophilia (TPE) is a parasitic lung disease.
- Pulmonary function abnormalities are common in TPE.
Purpose of the Study:
- To analyze pulmonary function abnormalities in TPE patients.
- To assess the impact of diethylcarbamazine (DEC) treatment on TPE-related lung function changes.
Main Methods:
- Pulmonary function tests were conducted on ten TPE patients.
- Patients were treated with diethylcarbamazine (DEC).
- Pulmonary function was reassessed after treatment.
Main Results:
- Four patients showed mild obstructive patterns.
- Three patients exhibited restrictive patterns.
- One patient had a combined defect; two had normal function.
- Pulmonary function normalized in most patients post-DEC treatment.
- One patient had persistent mild obstructive defect.
Conclusions:
- TPE is associated with diverse pulmonary function abnormalities.
- Diethylcarbamazine (DEC) is effective in reversing lung function impairment in TPE.
- Persistent obstructive defects may occur in a subset of patients.
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