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Related Experiment Videos

Keratotic melanocytic nevus.

O Gurbuz1, R M Hurwitz

  • 1Department of Dermatology, Marmara University School of Medicine, Istanbul, Turkey.

International Journal of Dermatology
|December 1, 1990
PubMed
Summary

Keratotic melanocytic nevi, often from women's trunks, show a distinct infundibular pattern. This common finding in 35% of nevi warrants further attention in dermatopathology.

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Area of Science:

  • Dermatopathology
  • Histopathology
  • Dermatology

Background:

  • Melanocytic nevi are common skin lesions.
  • Specific architectural patterns within nevi are crucial for diagnosis.
  • The infundibular pattern in keratotic nevi has been underemphasized.

Purpose of the Study:

  • To describe the prevalence and characteristics of keratotic epithelial architectural patterns in melanocytic nevi.
  • To highlight the infundibular pattern as a significant feature.
  • To review clinical and histopathologic findings and relevant literature.

Main Methods:

  • Histopathologic examination of 363 melanocytic nevi.
  • Identification and classification of epithelial architectural patterns.
  • Literature review on keratotic melanocytic nevi.

Main Results:

  • Thirty-five percent (35%) of melanocytic nevi exhibited a keratotic epithelial architectural pattern.
  • The predominant pattern observed was infundibular.
  • These nevi were frequently located on the trunk of female patients and often associated with intradermal nevi.

Conclusions:

  • A significant proportion of melanocytic nevi display a keratotic, predominantly infundibular, architectural pattern.
  • This pattern, particularly in intradermal nevi on female trunks, is a notable finding.
  • Further recognition of this pattern is important for accurate dermatopathologic diagnosis.

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