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Related Experiment Video

Updated: May 21, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
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Published on: April 12, 2017

Immunotherapy in renal diseases.

Ajay Kher1, Vijay Kher

  • 1The Transplant Institute, Beth Israel Deaconess Medical Center, 110 Francis Street, 7th Floor, Boston, MA 02215, USA. akher@bidmc.harvard.edu

The Medical Clinics of North America
|June 19, 2012
PubMed
Summary
This summary is machine-generated.

Immunotherapy offers effective treatments for various glomerular diseases, including minimal change disease and lupus nephritis. This review details the use of immunosuppression for these and other serious kidney conditions.

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Area of Science:

  • Nephrology
  • Immunology

Background:

  • Immunotherapy has a long history in treating renal diseases with ongoing advancements.
  • Glomerular diseases represent a significant area of focus within renal pathology.

Purpose of the Study:

  • To review the application of immunotherapy in managing glomerular diseases.
  • To discuss the role of immunosuppression in specific glomerular conditions.

Main Methods:

  • Literature review of immunotherapy and immunosuppression in glomerular diseases.
  • Synthesis of current treatment strategies for various nephropathies.

Main Results:

  • Immunosuppression is a key therapeutic approach for numerous glomerular diseases.
  • Effective immunotherapy strategies exist for conditions like minimal change disease, lupus nephritis, and ANCA-associated vasculitis.

Conclusions:

  • Immunotherapy, particularly immunosuppression, is crucial for managing a spectrum of glomerular diseases.
  • Continued research in immunotherapy holds promise for improving outcomes in renal disease treatment.