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Updated: May 21, 2026

Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape
Published on: January 8, 2014
Fabrication of a hybrid microfluidic system incorporating both lithographically patterned microchannels and a 3D
Leon M Bellan1, Tatiana Kniazeva, Ernest S Kim
1Massachusetts Institute of Technology, 77 Massachussetts Avenue, The David H. Koch Institute, Cambridge, MA 02139, USA. Lbellan@mit.edu
Abstract:
A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.
