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Updated: May 21, 2026

Vessel-sparing Excision and Primary Anastomosis
Published on: January 7, 2019
[Posterior urethral valves--diagnosis and primary treatment considerations]
1Clinica de Chirurgie PediatricS, Spitalul Clinic de Urgenţă pentru Copii Maria Sklodowska Curie, U.M.F. Carol Davila, Bucureşti România. simiontirlea@gmail.com
Insights
Posterior urethral valves (PUV) are a common cause of bladder obstruction in male infants. Endoscopic valve ablation is an effective first-line treatment, significantly reducing mortality and improving patient outcomes.
Area of Science:
- Pediatric Urology
- Medical Engineering
Context:
- Posterior urethral valves (PUV) are the primary cause of bladder outflow obstruction in male infants.
- PUV accounts for approximately 10% of prenatally detected hydronephrosis cases.
Purpose:
- To evaluate endoscopic valve ablation as the primary treatment for PUV.
- To analyze the long-term outcomes and morbidity associated with PUV.
Summary:
- A review of 27 male infants treated for PUV between 2001-2010.
- Endoscopic valve ablation demonstrated a 96% survival rate with favorable serum creatinine levels.
- Mortality rates for PUV have declined significantly over the past 30 years.
Impact:
- Endoscopic valve ablation offers a successful first-choice treatment for PUV.
- Improved survival rates and reduced morbidity highlight advancements in pediatric urology.
- Urodynamic studies are crucial for understanding long-term urinary tract effects.
Abstract:
Posterior Urethral Valves--PUV are the most common cause of bladder outflow obstruction in male infants, representig about 10% of prenatally detected hydronephrosis. The medical records of 27 patients, admitted and treated in the pediatric urology department of "Maria Sklodowska Curie" Emergency Hospital for Children, Bucharest, between 2001-2010 where reviewed. The aim of the study is to discuss the endoscopic valve ablation as the first choice treatment of PUV. Twenty-six, (96%) of ouer patients are alive, having now different ages, with serum creatinine levels < 0.8 mg/dl, at successive controls. One patient, lyear 11 mounths old, died in the pediatric nephrology department after right nephrec-tomy and left ureterostomy, 9 mounth before. Mortality rate in PUV patients has significantly decreased in the last 30 years, from 50% to less than 10% of patients. Nonetheless, morbidity related to PUV still represent an heavy burden for these patients and their doctors. Urodynamic studies help in understanding the pathophysiology of valve bladder and its effect on the urinary tract at long term follow-up.
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