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[Recurrent toxin-mediated perineal erythema in an 11-year-old child]
A Schoeffler1, M Bollaert, P Muller
1Service de dermatologie, hôpital Beauregard, CHR de Metz-Thionville, 21, rue des Frères, 57100 Thionville, France. amelie.schoeffler@free.fr
Insights
Recurrent toxin-mediated perineal erythema, a rare condition, can present with pustular lesions in children. Prompt antibiotic treatment is crucial for managing this staphylococcal or streptococcal toxin-induced rash.
Area of Science:
- Pediatric Dermatology
- Toxicology
- Infectious Diseases
Background:
- Recurrent perineal erythema is a rare toxin-mediated disease.
- It is typically caused by superantigens from Staphylococcus or Streptococcus species.
- This condition often presents as recurrent macular erythema of the perineum.
Observation:
- A case of recurrent toxin-mediated perineal erythema in an 11-year-old boy is presented.
- The patient experienced an erythematous pustular eruption on the perineum and axillae following pharyngotonsillitis.
- A previous episode of pharyngotonsillitis had also been associated with a similar cutaneous eruption.
Findings:
- Laboratory analysis confirmed recurrent toxin-mediated perineal erythema.
- The skin disorder showed rapid improvement with treatment.
- Antistreptococcal antibiotic therapy was initiated to eradicate bacteria.
Implications:
- This case highlights atypical pustular presentations of toxin-mediated erythema.
- Dermatologists should consider this diagnosis in children with recurrent perineal rashes.
- Early identification of bacterial toxins and appropriate antibiotic use are essential for effective management.
Introduction:
Recurrent perineal erythema is a rare toxin-mediated disease. We report the case of recurrent toxin-mediated perineal erythema in a child.
Case Report:
An 11-year-old boy was hospitalized for erythematous pustular eruption involving the perineum and the axillary area. This erythema started a few days after the onset of pharyngotonsillitis and the patient's personal history involved another episode of pharyngotonsillitis which was followed by an identical cutaneous eruption. Laboratory analysis confirmed the diagnosis of recurrent toxin-mediated perineal erythema. The skin disorder quickly improved and antistreptococcal antibiotic treatment was initiated to eradicate bacteria.
Discussion:
Recurrent toxin-mediated perineal erythema is a cutaneous disease mediated by superantigens which are toxins produced by staphylococci and streptococci. It is characterized by recurrent macular erythema involving the perineum. Streptococcus pyogenes is the most common cause of recurrent toxin-mediated perineal erythema, with Staphylococcus aureus being isolated most rarely. This observation emphasizes the possibility of atypical clinical presentation with pustular lesions, and dermatologists must be mindful of this aetiology in order to isolate bacterial toxins and to initiate appropriate antibiotics.
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