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Related Concept Videos

Cardiovascular Drugs: Classification based on Therapeutic Indications01:18

Cardiovascular Drugs: Classification based on Therapeutic Indications

Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However, frequent irregular...
Ischemic Heart Disease: Overview01:17

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and narrowing...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Coronary Artery Disease IV: Preventive Measures01:26

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Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
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Assessment of the Cardiovascular System I: Subjective Data

A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
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Published on: September 26, 2018

Cardiovascular disease in India.

Tester F Ashavaid1, Chandrashekhar K Ponde, Swarup Shah

  • 1Department of Laboratory Medicine, P.D. Hinduja National Hospital and Medical Research Center, Veer Savarkar Marg, Mahim, Mumbai, Maharashtra, India. dr_tashavaid@hindujahospital.com

Clinics in Laboratory Medicine
|June 26, 2012
PubMed
Summary

Young Indians face high cardiac risk from cardiovascular disease (CVD). Biomarker and genetic marker evaluation is crucial for early detection and risk assessment in this population.

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Area of Science:

  • Cardiology
  • Genetics
  • Public Health

Background:

  • Cardiovascular disease (CVD) is a leading cause of mortality in India.
  • Young Indians (under 40) exhibit a high cardiac risk, with millions affected.
  • Early assessment of cardiac risk in young Indians is a significant public health concern.

Purpose of the Study:

  • To evaluate biomarkers associated with acute coronary syndrome (ACS), inflammation, ischemia, and heart failure in Indian subjects.
  • To identify novel genetic markers for cardiovascular disease (CVD) risk assessment.
  • To develop a diagnostic assay for screening young, asymptomatic Indian individuals at risk for CVD.

Main Methods:

  • Biomarker analysis at various stages of cardiovascular disease, including inflammation, ischemia, and heart failure.
  • Utilizing candidate gene and/or genome-wide association studies to identify genetic markers.
  • Developing a diagnostic assay for early CVD risk screening.

Main Results:

  • Biomarker evaluation aids in assessing cardiac risk in Indian subjects.
  • Identification of genetic markers can improve diagnostic capabilities.
  • The study highlights the need for targeted screening in young Indian populations.

Conclusions:

  • Biomarker and genetic marker research is essential for understanding and managing CVD in young Indians.
  • Developing effective diagnostic tools can facilitate early detection and intervention.
  • Addressing the high cardiac risk in young Indians requires a multi-faceted approach including genetic screening.