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Hydra, a Computer-Based Platform for Aiding Clinicians in Cardiovascular Analysis and Diagnosis
Published on: September 26, 2018
Cardiovascular disease in India
Tester F Ashavaid1, Chandrashekhar K Ponde, Swarup Shah
1Department of Laboratory Medicine, P.D. Hinduja National Hospital and Medical Research Center, Veer Savarkar Marg, Mahim, Mumbai, Maharashtra, India. dr_tashavaid@hindujahospital.com
Insights
Young Indians face high cardiac risk from cardiovascular disease (CVD). Biomarker and genetic marker evaluation is crucial for early detection and risk assessment in this population.
Area of Science:
- Cardiology
- Genetics
- Public Health
Background:
- Cardiovascular disease (CVD) is a leading cause of mortality in India.
- Young Indians (under 40) exhibit a high cardiac risk, with millions affected.
- Early assessment of cardiac risk in young Indians is a significant public health concern.
Purpose of the Study:
- To evaluate biomarkers associated with acute coronary syndrome (ACS), inflammation, ischemia, and heart failure in Indian subjects.
- To identify novel genetic markers for cardiovascular disease (CVD) risk assessment.
- To develop a diagnostic assay for screening young, asymptomatic Indian individuals at risk for CVD.
Main Methods:
- Biomarker analysis at various stages of cardiovascular disease, including inflammation, ischemia, and heart failure.
- Utilizing candidate gene and/or genome-wide association studies to identify genetic markers.
- Developing a diagnostic assay for early CVD risk screening.
Main Results:
- Biomarker evaluation aids in assessing cardiac risk in Indian subjects.
- Identification of genetic markers can improve diagnostic capabilities.
- The study highlights the need for targeted screening in young Indian populations.
Conclusions:
- Biomarker and genetic marker research is essential for understanding and managing CVD in young Indians.
- Developing effective diagnostic tools can facilitate early detection and intervention.
- Addressing the high cardiac risk in young Indians requires a multi-faceted approach including genetic screening.
Abstract:
Cardiovascular disease (CVD) is one of the leading cause of mortality in India. It is estimated that 23.6 million CVD cases will be reported in subjects younger than 40 years of age by 2015, suggesting that young Indians are at higher cardiac risk. Evaluation of biomarkers in acute coronary syndrome (ACS) and at various stages of the disease such as inflammation, ischemia, and heart failure would indeed help to assess cardiac risk in Indian subjects. Identification of newer genetic markers through the candidate and/or genome-wide association approach would prove to be beneficial in developing a diagnostic assay for screening young asymptomatic Indian subjects.
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Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...