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Updated: May 21, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

meso-arylporpholactones and their reduction products

Christian Brückner1, Junichi Ogikubo, Jason R McCarthy

  • 1Department of Chemistry, University of Connecticut, Storrs, Connecticut 06269-3060, USA. c.bruckner@uconn.edu

The Journal of Organic Chemistry
|June 28, 2012
PubMed
Summary

This study details the synthesis of porpholactones and their analogues through a two-step process involving porphyrin modification. These novel compounds exhibit unique photophysical properties due to the oxazolone or oxazole moiety, impacting their electronic characteristics.

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