Linear and nonlinear analysis of airflow recordings to help in sleep apnoea-hypopnoea syndrome diagnosis
Related Experiment Video
Updated: May 21, 2026

A Model to Simulate Clinically Relevant Hypoxia in Humans
Published on: December 22, 2016
G C Gutiérrez-Tobal1, R Hornero, D Alvarez
1Biomedical Engineering Group, ETSI de Telecomunicación, University of Valladolid, Paseo Belén 15, 47011, Valladolid, Spain. gguttob@ribera.tel.uva.es
Abstract:
This paper focuses on the analysis of single-channel airflow (AF) signal to help in sleep apnoea-hypopnoea syndrome (SAHS) diagnosis. The respiratory rate variability (RRV) series is derived from AF by measuring time between consecutive breathings. A set of statistical, spectral and nonlinear features are extracted from both signals. Then, the forward stepwise logistic regression (FSLR) procedure is used in order to perform feature selection and classification. Three logistic regression (LR) models are obtained by applying FSLR to features from AF, RRV and both signals simultaneously. The diagnostic performance of single features and LR models is assessed and compared in terms of sensitivity, specificity, accuracy and area under the receiver-operating characteristics curve (AROC). The highest accuracy (82.43%) and AROC (0.903) are reached by the LR model derived from the combination of AF and RRV features. This result suggests that AF and RRV provide useful information to detect SAHS.
More Related Videos
Related Concept Videos
Application of Integration: Problem Solving
Application of Linearization and Approximation
Sleep Apnea
The condition is more prevalent among...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Chronic Obstructive Pulmonary Disease-IV: Assessement and Diagnostic Studies
Medical History

