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Updated: May 21, 2026

Murine Ileocolic Bowel Resection with Primary Anastomosis
Published on: October 29, 2014
[Clinical study of different bowel preparations on changes of gut flora in patients undergoing colorectal resection]
Ying-jun Wu1, Cheng-tang Wu, Xiao-bin Zhang
1Department of General Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, China.
Objective:
To compare the impact of traditional and fast bowel preparation on the changes of gut flora in the patients following colorectal resection.
Methods:
Sixty patients undergoing colorectal resection from March 2010 to March 2011 in the Nanfang Hospital were randomly divided into the control group(n=27, 3 days of bowel preparation) and the experimental group(n=33, 1 day of bowel preparation). Fresh feces were collected before bowel preparation and on the first defecation after surgery. The postoperative changes in gut flora and septic complications were observed.
Results:
Gut flora disturbance was found in both groups. The postoperative population of Bifidobacterium and Lactobacillus decreased significantly(P<0.05), and the decrease was more significant in the experimental group compared to the control group(P<0.05), while E.coli and Staphylococcus were much higher than the preoperative level(P<0.05), which was more significant in the control group. The incidence of postoperative infection was 9.1%(3/33) in the experimental group, which was significantly lower than 29.6%(8/27) in the control group(P<0.05).
Conclusion:
Fast bowel preparation is effective in reducing gut flora disturbance and the incidence of postoperative infection.
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