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Updated: May 21, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Rationale for antimicrobial prophylaxis in surgery and its implementation in Finnish patient care]
1TYKS, kirurgian klinikka.
Abstract:
Country-specific differences in bacterial antibiotic resistances cause variability in recommendations given in different countries. Mutually approved national expert and hospital-specific practices are therefore beneficial. Selection of the best prophylactic antimicrobial drug and correct timing of drug dosing are of high significance. In the light of our questionnaire survey prophylactic practices are relatively consistent in Finland. Hospitals have operation-specific recommendations on prophylaxis, but adherence to them is scarcely monitored. In fact, hospitals should invest in such monitoring systems.
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