Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...

Peripheral Artery Disease I: Introduction

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

Herniated Intervertebral Disc l: Introduction

Herniated Intervertebral Disc l: Introduction

Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

Spinal Cord Injury ll: Pathophysiology

Spinal Cord Injury ll: Pathophysiology

Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Extracorporeal membrane oxygenation experience in COVID-19 pandemic: Report of two cases.

Northern clinics of Istanbul·2022

Same author

Effects of multimedia nursing education on disease-related depression and anxiety in patients staying in a coronary intensive care unit.

Applied nursing research : ANR·2016

Same author

A fatal complication after repair of post-infarction ventricular septal rupture: heparin-induced thrombocytopenia with thrombosis.

Cardiovascular journal of Africa·2015

Same author

Relationship Between Mean Platelet Volume and Pulmonary Embolism in Patients With Deep Vein Thrombosis.

Heart, lung & circulation·2015

Same author

Increased Mean Platelet Volume in Familial Hypercholesterolemia.

Angiology·2015

Same author

Neuroprotective effect of atorvastatin in spinal cord ischemia-reperfusion injury.

Clinics (Sao Paulo, Brazil)·2015

Search research articles

Related Experiment Video

Updated: May 21, 2026

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Published on: March 3, 2014

Painless aortic dissection presenting as paraplegia.

Necmettin Colak¹, Yunus Nazli, Mehmet Fatih Alpay

¹Department of Cardiovascular Surgery, School of Medicine, Fatih University, 06510 Ankara, Turkey. ncolak06@yahoo.com

Texas Heart Institute Journal

|June 29, 2012

Summary

Sudden paraplegia and leg ischemia can signal rare aortic dissection. Prompt diagnosis and surgical repair of acute aortic dissection are crucial for preventing severe outcomes.

Keywords:

Aneurysm, dissecting/complications/diagnosis/surgery aortic aneurysm/complications/diagnosis/surgery diagnosis, differential extremities/blood supply ischemia/complications pain/physiopathology paraplegia/etiology/physiopathology spinal cord ischemia/etiology/surgery treatment outcome

More Related Videos

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Published on: July 22, 2017

Related Experiment Videos

Last Updated: May 21, 2026

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Published on: March 3, 2014

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Novel and Innovative Hybrid Technique for Type A Aortic Dissection

Published on: March 28, 2025

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Reproducible Motor Deficit Following Aortic Occlusion in a Rat Model Of Spinal Cord Ischemia

Published on: July 22, 2017

Area of Science:

Cardiovascular Surgery
Neurology
Vascular Surgery

Background:

Acute aortic dissection is a life-threatening condition.
Neurologic complications, including paraplegia, are uncommon presentations of aortic dissection.

Observation:

A 51-year-old male with a history of coronary artery bypass grafting presented with sudden paraplegia and leg ischemia, notably absent chest or back pain.
Physical examination revealed pulseless lower extremities, and computed tomography confirmed extensive aortic dissection.
The patient underwent cerebrospinal fluid drainage and cardiopulmonary bypass for aortic dissection repair and coronary graft reattachment.

Findings:

Surgical intervention successfully restored spinal and lower-extremity perfusion.
The patient recovered significantly, walking unaided upon discharge.

Implications:

Acute aortic dissection should be considered in patients presenting with sudden paraplegia and pulseless lower extremities, even without chest or back pain.
Early diagnosis and intervention are critical for improving outcomes and preventing mortality in cases of aortic dissection with neurologic compromise.