Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Raman Spectroscopy: Overview01:20

Raman Spectroscopy: Overview

The underlying principle of Raman spectroscopy is based on the interaction between light and matter, specifically molecules' inelastic scattering of photons. When a monochromatic beam of light, typically from a laser source, interacts with a sample, most scattered light has the same frequency as the incident light. This is known as Rayleigh scattering.
However, a small fraction of the scattered light exhibits a frequency shift due to the exchange of energy between the incident photons and the...
Raman Spectroscopy Instrumentation: Overview01:26

Raman Spectroscopy Instrumentation: Overview

A conventional Raman spectrophotometer includes a laser source, a sample holding system, a wavelength selector, and a detector.
The monochromatic laser source, typically using visible or near-infrared radiation, generates a highly focused beam of light. This light interacts with the molecules of the sample, scattering some of the light. Liquid and gaseous samples are usually tested in ordinary glass capillaries, while solids can be analyzed as powders packed in capillaries or as potassium...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Eosinophilic myocarditis: diagnostic pitfalls and therapeutic challenges. A Case Series.

Frontiers in cardiovascular medicine·2026
Same author

Webbed left atrial septal pouch mimicking septal abnormality on imaging: a case report.

Hong Kong medical journal = Xianggang yi xue za zhi·2026
Same author

Izalontamab brengitecan (Iza-bren; BL-B01D1), a first-in-class EGFR-HER3 bispecific antibody-drug conjugate, for patients with EGFR-mutated NSCLC: pooled analysis of phase I and phase II trials.

Annals of oncology : official journal of the European Society for Medical Oncology·2026
Same author

DATA RETRIEVAL FOR CLINICAL PROJECTS IN THE EVOLVING HEALTHCARE SYSTEM: PAST, PRESENT, AND FUTURE.

Georgian medical news·2026
Same author

Genome-wide association study implicates possible causal genes for growth, fatness, and reproductive traits in pig.

Animal : an international journal of animal bioscience·2025
Same author

Retrospective multicenter study on cryptogenic NORSE/FIRES patients treated with anakinra.

Seizure·2025
Same journal

Gaussian-modulated continuous-variable quantum key distribution over 60 km fiber using an integrated silicon photonic receiver.

Optics letters·2026
Same journal

E2E-OCT: end-to-end joint learning model using optical coherence tomography images for vocal cord leukoplakia diagnosis.

Optics letters·2026
Same journal

Holographic generation of panoramic 3D scenes by concave ellipsoidal mirror reflection.

Optics letters·2026
Same journal

Dual-pilot phase recovery with pair-wise maximum-ratio combining for coherent PONs.

Optics letters·2026
Same journal

Mapping the whispering gallery modes of a CaF<sub>2</sub> disk resonator with half-tapered fibers to estimate the fundamental mode volume.

Optics letters·2026
Same journal

Quantitative estimation of deep-subwavelength scale via dark-field scattering axial energy concentration decay profiles.

Optics letters·2026
See all related articles

Related Experiment Video

Updated: May 21, 2026

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
13:48

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

Published on: May 29, 2012

Surface-enhanced Raman spectroscopy: nonlocal limitations.

G Toscano1, S Raza, S Xiao

  • 1Department of Photonics Engineering, Technical University of Denmark, DK-2800 Kgs. Lyngby, Denmark.

Optics Letters
|June 30, 2012
PubMed
Summary
This summary is machine-generated.

A new nonlocal model reveals fundamental limits on plasmonic field enhancement, impacting surface-enhanced Raman spectroscopy (SERS). This approach prevents infinite enhancements, even with sharp features, by considering electron gas properties.

More Related Videos

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

Label-Free Surface-Enhanced Raman Scattering Bioanalysis Based on Au@Carbon Dot Nanoprobes
06:19

Label-Free Surface-Enhanced Raman Scattering Bioanalysis Based on Au@Carbon Dot Nanoprobes

Published on: June 9, 2023

Related Experiment Videos

Last Updated: May 21, 2026

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy
13:48

Non-contact, Label-free Monitoring of Cells and Extracellular Matrix using Raman Spectroscopy

Published on: May 29, 2012

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging
09:46

Direct Comparison of Hyperspectral Stimulated Raman Scattering and Coherent Anti-Stokes Raman Scattering Microscopy for Chemical Imaging

Published on: April 28, 2022

Label-Free Surface-Enhanced Raman Scattering Bioanalysis Based on Au@Carbon Dot Nanoprobes
06:19

Label-Free Surface-Enhanced Raman Scattering Bioanalysis Based on Au@Carbon Dot Nanoprobes

Published on: June 9, 2023

Area of Science:

  • Plasmonics and Nanophotonics
  • Surface-Enhanced Raman Spectroscopy (SERS)

Background:

  • Local-response models predict giant field enhancements and singularities in plasmonic nanostructures.
  • These predictions are crucial for understanding phenomena like SERS.

Purpose of the Study:

  • To investigate the impact of a nonlocal treatment on plasmonic field enhancement.
  • To establish fundamental limitations on field enhancement and their consequences for SERS.

Main Methods:

  • Developed a more general nonlocal treatment of plasmonic response.
  • Modeled silver nanogroove structures using periodic arrays of half-cylinders (up to 120 nm radius).

Main Results:

  • Nonlocal treatment smears out field singularities predicted by local models.
  • Finite, not infinite, SERS enhancement factors were found, even for sharp geometries.
  • Maximum enhancement factors were limited to 10 orders of magnitude (10^10) for the studied silver nanostructures.

Conclusions:

  • Nonlocal effects impose fundamental limitations on plasmonic field enhancement.
  • The intrinsic electron gas length scale is critical for accurate SERS enhancement predictions.
  • Infinite field enhancements are an artifact of oversimplified local-response models.