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Published on: April 6, 2017
[Inhaled corticosteroids and behavioural changes in children]
Nancy Broos1, Tjalling W de Vries, Eric J Duiverman
1Universitair Medisch Centrum, afd. Klinische Farmacie, Utrecht, the Netherlands. nancybroos@hotmail.com
Insights
Inhaled corticosteroids can cause behavioral changes like aggression and mood swings in children. Early recognition of these side effects is crucial for proper management and to avoid unnecessary medical tests.
Area of Science:
- Pediatric medicine
- Pharmacology
Background:
- Inhaled corticosteroids (ICS) are a common treatment for pediatric respiratory conditions.
- Adverse drug reactions, including behavioral changes, can occur with ICS use.
Observation:
- Two pediatric patients, a 7-year-old boy and a 9-year-old girl, exhibited behavioral changes.
- These changes included hyperactivity, aggression, mood swings, and agitation.
Findings:
- The observed behavioral changes were linked to the use of inhaled corticosteroids.
- These side effects are reversible upon recognition and potential adjustment of treatment.
Implications:
- Timely recognition of ICS-induced behavioral changes is essential in pediatric care.
- Awareness can prevent misdiagnosis, unnecessary investigations, and psychosocial problems for children.
- Healthcare providers should consider behavioral side effects when prescribing inhaled corticosteroids to children.
Abstract:
Behavioural changes, such as hyperactivity, aggression, mood swings and agitation may occur during the use of inhaled corticosteroids. Children are particularly vulnerable to this possible adverse drug reaction. As this side effect is reversible, timely recognition is important in order to prevent unnecessary diagnostic investigations and problems at home or at school. In this article we present two patients, a seven-year-old boy and a nine-year-old girl, who illustrate the importance of awareness of this unwanted effect of inhaled corticosteroids.
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