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[Optic nerve atrophy with particular attention to perinatal damage]
J R Petersen1, T Rosenberg, K K Ibsen
1Statens Ojenklinik, Hellerup, Synsregisteret.
Ugeskrift for Laeger
|December 17, 1990
Summary
Perinatal stress, including prematurity and asphyxia, is a significant cause of optic atrophy in children, often accompanied by other developmental challenges. Early diagnosis and intervention are crucial for improving outcomes in visually impaired infants.
Area of Science:
- Ophthalmology
- Pediatrics
- Neurology
Context:
- Optic atrophy is a leading cause of visual impairment in children.
- Understanding the etiology of optic atrophy is crucial for effective management and prevention.
- This study investigates the link between perinatal factors and optic atrophy in a Danish cohort.
Purpose:
- To identify the causes of optic atrophy in children born between 1983 and 1987.
- To determine the prevalence of perinatal stress factors in children with optic atrophy.
- To highlight the association between optic atrophy, perinatal damage, and additional handicaps.
Summary:
- A review of 55 children diagnosed with optic atrophy revealed known or presumed etiologies in 53 cases.
- Perinatal stress factors were identified in 58% of patients, with prematurity, low birth-weight, and perinatal asphyxia being most common.
- Children with optic atrophy due to perinatal issues frequently presented with multiple handicaps, including cerebral palsy, epilepsy, and psychomotor retardation.
Impact:
- Emphasizes the need for heightened awareness of visual impairment in multiply handicapped children.
- Underscores the importance of early diagnosis and educational stimulation for affected children.
- Suggests that visual impairment from perinatal damage is partially preventable through better etiological identification and understanding of infantile optic neuropathy pathogenesis.