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Related Concept Videos

Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
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Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
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Endocarditis II: Clinical Features of Infective Endocarditis

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Inflammatory Bowel Disease I: Introduction01:26

Inflammatory Bowel Disease I: Introduction

Inflammatory bowel disease is a group of chronic disorders marked by recurrent inflammation of the gastrointestinal tract due to an abnormal immune response against gut microflora. This leads to tissue damage. The two main forms are Crohn’s disease and ulcerative colitis.Crohn’s DiseaseCrohn’s disease is a relapsing inflammatory disorder that can affect any part of the GI tract, from the mouth to the anus. It involves all layers of the bowel wall (transmural) and shows “skip lesions” in which...
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

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Inflammatory Bowel Disease II: Ulcerative Colitis

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Related Experiment Video

Updated: May 20, 2026

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Recurrent Kikuchi-Fujimoto disease.

Brendan Boyd Spooner1, Imdadur Rahman, Nigel Langford

  • 1City Hospital, Birmingham, UK. bspooner@doctors.org.uk

BMJ Case Reports
|July 4, 2012
PubMed
Summary
This summary is machine-generated.

This case study details a rare recurrence of Kikuchi-Fujimoto disease in a young woman. High-dose prednisolone effectively treated the recurrent symptoms, highlighting its potential in managing severe cases.

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Last Updated: May 20, 2026

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK
07:27

Recurrent Herpetic Stromal Keratitis in Mice, a Model for Studying Human HSK

Published on: December 18, 2012

Area of Science:

  • Medicine
  • Immunology

Background:

  • Kikuchi-Fujimoto disease is a rare, benign, self-limiting condition characterized by lymphadenopathy and fever.
  • Recurrence is uncommon, and presentation at different body sites is unusual.

Observation:

  • A 27-year-old woman experienced a second episode of Kikuchi-Fujimoto disease, presenting with cervical lymphadenopathy and fever.
  • Initial treatment with paracetamol and NSAIDs was ineffective.

Findings:

  • A cervical lymph node biopsy confirmed recurrent Kikuchi-Fujimoto disease.
  • High-dose prednisolone rapidly resolved symptoms, pyrexia, and inflammatory markers within 24 hours.
  • The patient's condition improved steadily with gradual steroid reduction over nine months.

Implications:

  • This case underscores the potential for rare recurrences of Kikuchi-Fujimoto disease.
  • High-dose corticosteroids may be a viable treatment option for severe or recurrent cases.
  • Further research into the management of recurrent Kikuchi-Fujimoto disease is warranted.