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Experimental Tibetan monkey domestication and its application for intraocular pressure measurement
Yong Yi1, Tao Zeng, Liang Zhou
1Institute of Laboratory Animals of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, Chengdu 610212, Sichuan Province, China.
Aim:
To train Tibetan monkey (Macaca thibetana) for intraocular pressure (IOP) measurement in conscious state and obtain normal IOP in conscious Tibetan Macaque.
Methods:
The training was based on award-conditioned behavior. Food stimulation and human-animal interaction were used in this training.
Results:
Trained Tibetan monkeys calmly accepted IOP measurement by the TonoVet® rebound tonometer without sedation or anesthesia and their IOP values were similar to other primates.
Conclusion:
Human-cultivated Thibetan monkeys are tamable, and can be used for biomedical research such as ophthalmic research without anesthesia.
