Hemodynamic findings of spontaneously recanalized coronary thrombus

Jeffery Cook1, Abhishek Deshmukh, Rajesh Sachdeva

  • 1Department of Medicine, Division of Cardiology, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.

Insights

This case study details a patient experiencing non-ST elevation myocardial infarction. The cause was a recanalized thrombus in a coronary artery, confirmed by fractional flow reserve.

Area of Science:

  • Cardiology
  • Interventional Cardiology

Background:

  • Non-ST elevation myocardial infarction (NSTEMI) is a common presentation of acute coronary syndrome.
  • Coronary artery thrombus formation is a primary driver of myocardial infarction.

Observation:

  • A patient presented with NSTEMI.
  • Coronary angiography revealed a linear opacity in a coronary artery, not flow-limiting.
  • Fractional flow reserve (FFR) measurements indicated ischemia.

Findings:

  • The linear opacity was identified as a recanalized organized thrombus.
  • The thrombus, despite not being flow-limiting on initial assessment, was the cause of ischemic FFR values.

Implications:

  • This case highlights that even non-flow-limiting coronary artery lesions can cause myocardial infarction.
  • Recanalized thrombi should be considered in the differential diagnosis of NSTEMI with non-obstructive coronary findings.
  • FFR is crucial in assessing the functional significance of coronary artery abnormalities.