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Updated: May 20, 2026

A Thrombotic Stroke Model Based On Transient Cerebral Hypoxia-ischemia
Published on: August 18, 2015
Hemodynamic findings of spontaneously recanalized coronary thrombus
Jeffery Cook1, Abhishek Deshmukh, Rajesh Sachdeva
1Department of Medicine, Division of Cardiology, Central Arkansas Veterans Healthcare System, Little Rock, AR, USA.
Insights
This case study details a patient experiencing non-ST elevation myocardial infarction. The cause was a recanalized thrombus in a coronary artery, confirmed by fractional flow reserve.
Area of Science:
- Cardiology
- Interventional Cardiology
Background:
- Non-ST elevation myocardial infarction (NSTEMI) is a common presentation of acute coronary syndrome.
- Coronary artery thrombus formation is a primary driver of myocardial infarction.
Observation:
- A patient presented with NSTEMI.
- Coronary angiography revealed a linear opacity in a coronary artery, not flow-limiting.
- Fractional flow reserve (FFR) measurements indicated ischemia.
Findings:
- The linear opacity was identified as a recanalized organized thrombus.
- The thrombus, despite not being flow-limiting on initial assessment, was the cause of ischemic FFR values.
Implications:
- This case highlights that even non-flow-limiting coronary artery lesions can cause myocardial infarction.
- Recanalized thrombi should be considered in the differential diagnosis of NSTEMI with non-obstructive coronary findings.
- FFR is crucial in assessing the functional significance of coronary artery abnormalities.
Abstract:
This case presented is a patient with non-ST elevation myocardial infarction with angiographic non-flow limiting linear opacity in coronary artery with fractional flow reserve in ischemic range secondary to recanalized organized thrombus.

