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Published on: March 2, 2016
Preparation of concentrated colloids of gold core-silica shell nanoparticles for biomedical applications
1FIRST Research Center for Innovative Nanobiodevices, Nagoya University, Nagoya, Japan. yspman@gmail.com
Abstract:
Encapsulation of gold nanoparticles within a silica shell is highly beneficial to the preparation of highly concentrated gold nanoparticles that can strongly absorb X-ray and hence be used as an X-ray contrast agent. This chapter describes a method for preparing highly concentrated colloidal gold nanoparticles suitable for an X-ray contrast agent application. It describes specific details of procedures for preparing spherical gold nanoparticles, forming thin silica shell on each gold nanoparticle, and enriching the silica-encapsulated gold nanoparticles.

