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Enhanced enantioselectivity of 3-methylcyclohexanone by mixed diol host compounds

Luigi R Nassimbeni1, Hong Su, Tanith-Lea Curtin

  • 1Department of Chemistry, University of Cape Town, Rondebosch 7701, South Africa. Luigi.Nassimbeni@uct.ac.za

Chemical Communications (Cambridge, England)
|July 18, 2012
PubMed
Summary

Complete chiral resolution of 3-methylcyclohexanone was achieved using a novel crystallization method. This technique employs a mixture of chiral and achiral host compounds to enhance enantiomeric excess through kinetic effects.

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