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Antioxidant composition causes antiexsudorific effect in the model of chronic venous insufficiency
I S Ivanov1, A V Sidekhmenova, O I Aliev
1Institute of Pharmacology, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia.
Bulletin of Experimental Biology and Medicine
|July 18, 2012
Abstract:
Venous hypertension and swelling of the hind limbs was demonstrated to develop in rat model of chronic venous insufficiency. It was found that 14-day course of dihydroquercetin (50 mg/kg) and lipoic acid (50 mg/kg) administered intragastrically prevented the increase in hind limb volume and reduced the severity of edema of rat muscle tissue in chronic venous insufficiency.
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