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Updated: May 20, 2026

Determining Basal Energy Expenditure and the Capacity of Thermogenic Adipocytes to Expend Energy in Obese Mice
Published on: November 11, 2021
Effect of calorie restricted diet on brown adipose tissue in mice
E I Elsukova1, L N Medvedev, O V Mizonova
1Department of Biomedical Bases of Human Life, Faculty of Natural Sciences, V. P. Astaf'ev Krasnoyarsk State Pedagogical University, Russia. elsukova@kspu.ru
Abstract:
Calorie restricted diet (50% food intake of control animals) for 3 weeks decelerated weight gain in laboratory mice, reduced the weight of abdominal fat, and decreased the rate of oxygen consumption by brown adipose tissue. The relative weight of interscapular brown fat and protein content in it did not differ from the control. DNA content in brown fat in mice kept on calorie restricted diet increased by 93% compared with the control.
