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Focal Cerebral Ischemia Model by Endovascular Suture Occlusion of the Middle Cerebral Artery in the Rat
Published on: February 5, 2011
A new rat model of reversible global cerebral ischemia
N S Shcherbak1, M M Galagudza, A N Kuzmenkov
1V. A. Almazov Federal Center of the Heart, Blood, and Endocrinology, St. Petersburg, Russia. ShcherbakNS@yandex.ru
Bulletin of Experimental Biology and Medicine
|July 18, 2012
Abstract:
A new rat model of global cerebral ischemia-reperfusion was proposed via reversible occlusion of the major vessels originating from the aortic arch and supplying the brain. This technique can be used for the search and study of exogenous (pharmacological) and endogenous methods of brain protection from ischemia-reperfusion injury.
