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Immunohistochemical characteristics of desmoid tumors

E A Dubova1, T V Sidorenko, A I Shchyogolev

  • 1V. I. Kulakov Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health and Social Development of the Russian Federation, Moscow, Russia. dubovaea@gmail.com

Bulletin of Experimental Biology and Medicine
|July 18, 2012
PubMed

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The term desmosome derives from the Greek words "desmo" and "soma" meaning "adhesion bodies." This structure was first observed during the late 1800s and described as small, dense nodules in the epidermis. Desmosomes are button-like structures that help form an interlinked network of intermediate filaments across the cells. These junctions are  essential to hold cells together under mechanical stress and to maintain tissue integrity. Desmosomes are multi-protein complexes comprising desmosomal...