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Updated: May 20, 2026

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
Published on: March 25, 2022
Endoscopic ultrasound guided biliary drainage
Ilaria Tarantino1, Luca Barresi, Carlo Fabbri
1Ilaria Tarantino, Luca Barresi, Mario Traina, Unit of Gastroenterology and Digestive Endoscopy, ISMETT Mediterranean Institute for Transplantation and Advanced Specialized Therapies/University of Pittsburgh Medical Center, 54000 Palermo, Italy.
Endoscopic retrograde cholangiopancreatography (ERCP) can fail for bile duct and pancreatic duct stenosis. Endoscopic ultrasonography-guided biliary drainage offers a promising alternative with high success and low complication rates.
Area of Science:
- Gastroenterology
- Interventional Endoscopy
Background:
- Endoscopic retrograde cholangiopancreatography (ERCP) is standard for biliary and pancreatic duct stenosis.
- ERCP stent placement can fail due to anatomical challenges and impacted stones.
- Alternative drainage methods like PTBD and surgery have significant risks.
Purpose of the Study:
- To review the efficacy and safety of endoscopic ultrasonography-guided biliary drainage.
- To evaluate EUS-guided biliary drainage as an alternative to ERCP failure.
Main Methods:
- Literature review of published data on EUS-guided biliary drainage.
- Analysis of techniques including direct access and rendezvous procedures.
- Assessment of technical success rates and complication profiles.
Main Results:
- EUS-guided biliary drainage demonstrates technical success rates between 75%-100%.
- The procedure is associated with a low rate of complications.
- It serves as a viable alternative to percutaneous trans-hepatic biliary drainage (PTBD).
Conclusions:
- Endoscopic ultrasonography-guided biliary drainage is an effective and safe alternative for patients with failed ERCP.
- This technique offers a less invasive option compared to PTBD or surgery.
- EUS-guided drainage expands treatment options for complex biliary and pancreatic duct stenosis.
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