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Measuring Rates of Herbicide Metabolism in Dicot Weeds with an Excised Leaf Assay

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A weed by any other name.

Berdine M Burger¹, Pamela S Chavis, Valerie Purvin

¹Storm Eye Institute, Medical University of South Carolina, Charleston, SC, USA.

Survey of Ophthalmology

|July 24, 2012

Summary

Idiopathic intracranial hypertension was suspected in a patient with severe headaches and papilledema. Cerebral venous sinus stenosis, a potential cause of this condition, was diagnosed via angiography.

Area of Science:

Neurology
Vascular Neurology
Neuroimaging

Background:

Idiopathic intracranial hypertension (IIH) is a condition characterized by elevated intracranial pressure without a clear cause.
Intractable headaches and papilledema are common symptoms that can mimic other neurological disorders.
Standard diagnostic workup includes neuroimaging and cerebrospinal fluid analysis.

Observation:

A 39-year-old man presented with intractable headaches and papilledema.
Initial magnetic resonance imaging (MRI) and magnetic resonance venography (MRV) were normal.
Cerebrospinal fluid analysis revealed elevated protein levels, suggesting IIH, but the patient was refractory to medical treatment.

Findings:

Cerebral angiography identified cerebral venous sinus stenosis.

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The stenosis was presumed to be indicative of chronic cerebral venous sinus thrombosis.

This finding provided an alternative diagnosis for the patient's refractory symptoms.

Implications:

Cerebral venous sinus stenosis and thrombosis should be considered in cases of suspected IIH that are refractory to treatment.
Angiography is crucial for diagnosing venous sinus stenosis and thrombosis when initial imaging is inconclusive.
Accurate diagnosis of venous sinus abnormalities is essential for effective management and treatment of intracranial hypertension.