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Tryptophan metabolic studies in patients with presenile cataracts
1Department of Ophthalmology, Ernst-Moritz-Arndt University, Greifswald, GDR.
Biomedica Biochimica Acta
|January 1, 1990
Abstract:
In 43 patients with presenile cataracts an oral tryptophan loading test with 5 g L-tryptophan was performed and the 24-hour urinary excretion of kynurenine and xanthurenic acid was determined. 5 cases showed pathological deviations and an excretion pattern of tryptophan metabolites via kynurenine, similar as in vitamin B6-dependent xanthurenic aciduria.