Related Experiment Video
Updated: May 20, 2026
07:27
Robotic-assisted Left Pneumonectomy For Vanishing Lung Syndrome
Published on: January 23, 2026
Spontaneous globe luxation associated with chronic obstructive pulmonary disease
M Ashok Kumar1, K Srikanth, R Pandurangan
1Department of Ophthalmology, Mahatma Gandhi Medical College and Research Institute, Pillayarkupam, Puducherry, India.
Indian Journal of Ophthalmology
|July 25, 2012
Summary
Spontaneous globe luxation, a rare condition, can cause optic neuropathy. This report details a unique case linked to chronic obstructive pulmonary disease (COPD), a previously undocumented association.
Area of Science:
- Ophthalmology
- Pulmonology
- Medical Case Reports
Background:
- Spontaneous globe luxation is uncommon, with known associations including thyroid eye disease, shallow orbits, and floppy eyelid syndrome.
- Optic neuropathy is a potential complication of globe luxation, necessitating prompt diagnosis and management.
Observation:
- A patient presented with spontaneous globe luxation.
- The severity and onset of the luxation were notably associated with chronic obstructive pulmonary disease (COPD).
Findings:
- This case represents the first documented instance of spontaneous globe luxation linked to COPD.
- The findings suggest a potential, previously unrecognized association between respiratory disease severity and ocular emergencies.
Implications:
- This association may warrant increased ophthalmic surveillance in patients with severe COPD.
- Further research is needed to elucidate the pathophysiological mechanisms connecting COPD and spontaneous globe luxation.
- Clinicians should consider COPD as a potential contributing factor in cases of spontaneous globe luxation, especially in severe presentations.
Related Concept Videos
01:20Chronic Obstructive Pulmonary Disease-II: Pathophysiology
Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
Chronic Inflammation
01:24Chronic Obstructive Pulmonary Disease
COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
01:08Pneumothorax II: Pathophysiology
Pneumothorax means the presence of air in the pleural space — the thin potential gap between the visceral and parietal pleura. This condition disrupts the normal pressure balance that keeps the lungs inflated, leading to partial or complete collapse of the affected lung.Normal physiologyUnder normal conditions, the pleural space maintains a slightly negative intrapleural pressure, which keeps the lungs expanded against the chest wall. This negative pressure creates a delicate balance between...
01:25Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.
Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
01:23Chronic Obstructive Pulmonary Disease I: Introduction
Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...
01:19Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations
Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...