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Updated: May 20, 2026
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Metagenomic Analysis of Silage
Published on: January 13, 2017
DELIMINATE--a fast and efficient method for loss-less compression of genomic sequences: sequence analysis.
Monzoorul Haque Mohammed1, Anirban Dutta, Tungadri Bose
1Bio-sciences R&D Division, TCS Innovation Labs, Tata Consultancy Services Limited, 1 Software Units Layout, Madhapur, Hyderabad 500081, Andhra Pradesh, India.
Bioinformatics (Oxford, England)
|July 27, 2012
Summary
A new bioinformatics algorithm, DELIMINATE, offers efficient, lossless compression for large genomic sequence datasets generated by next-generation sequencing. DELIMINATE demonstrates superior compression performance compared to existing general-purpose tools.
Area of Science:
- Bioinformatics and Computational Biology
- Genomics and Molecular Biology
Background:
- Next-generation sequencing (NGS) platforms generate vast amounts of genomic data.
- Efficient management of large genomic datasets is crucial for analysis, storage, and transmission.
Purpose of the Study:
- To develop a novel bioinformatics algorithm for lossless compression of genomic sequence data.
- To improve the efficiency of handling large-scale genomic datasets.
Main Methods:
- Development of a novel compression algorithm named DELIMINATE.
- Validation of DELIMINATE's performance against established compression algorithms (gzip, bzip2, lzma).
Main Results:
- DELIMINATE achieves rapid, lossless compression of genomic sequence data.
- DELIMINATE exhibits higher compression efficiency compared to gzip, bzip2, and lzma.
Conclusions:
- DELIMINATE provides an effective solution for compressing large genomic datasets.
- The algorithm aids in the efficient storage, retrieval, and transmission of genomic data.
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