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Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...

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Modeling Brain Metastasis Via Tail-Vein Injection of Inflammatory Breast Cancer Cells
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Pregnancy and brain tumors.

Christopher M Bonfield1, Johnathan A Engh

  • 1Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA.

Neurologic Clinics
|July 31, 2012
PubMed
Summary

This article details the clinical presentation, diagnosis, and management of intracranial masses in pregnant patients, covering common symptoms and treatment guidelines.

Area of Science:

  • Neurology
  • Obstetrics & Gynecology
  • Neurosurgery

Background:

  • Intracranial masses during pregnancy present unique diagnostic and therapeutic challenges.
  • Maternal and fetal well-being must be balanced during management.

Purpose of the Study:

  • To review the clinical presentation, diagnostic approaches, and treatment strategies for intracranial masses in pregnant individuals.
  • To highlight common pitfalls and provide evidence-based guidelines for effective management.

Main Methods:

  • Literature review of clinical presentations, diagnostic imaging (MRI, CT), and treatment options (surgical, medical, conservative).
  • Discussion of neurosurgical considerations specific to pregnancy, including anesthetic and surgical risks.
  • Analysis of outcomes and follow-up protocols for mother and fetus.

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Main Results:

  • Common symptoms include headaches, seizures, and focal neurological deficits.
  • Diagnostic imaging is crucial, with MRI being the preferred modality due to safety.
  • Management strategies are individualized based on mass type, gestational age, and patient condition.

Conclusions:

  • Early diagnosis and multidisciplinary management are essential for optimal outcomes.
  • Treatment decisions require careful consideration of maternal neurological status and fetal development.
  • Adherence to established guidelines can mitigate risks associated with intracranial masses in pregnancy.