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Updated: May 19, 2026

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64×64 pixel smart sensor array for laser Doppler blood flow imaging.

D He¹, H C Nguyen, B R Hayes-Gill

¹Faculty of Engineering, University of Nottingham, University Park, Nottingham, UK.

|August 4, 2012

Summary

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This study demonstrates the first integrated two-dimensional CMOS imaging array for laser Doppler blood flow imaging. The novel sensor overcomes data bottlenecks, offering improved performance for blood flow monitoring.

Area of Science:

Biomedical Engineering
Optical Imaging
Sensor Technology

Background:

Laser Doppler blood flow imaging is crucial for monitoring tissue perfusion.
Existing systems face limitations due to data bottlenecks between sensors and processing units.
On-chip processing offers a potential solution to enhance efficiency and reduce system complexity.

Purpose of the Study:

To demonstrate the first fully integrated two-dimensional complementary metal oxide semiconductor (CMOS) imaging array specifically designed for laser Doppler blood flow imaging.
To overcome the data bottleneck issue prevalent in current commercial sensors.
To enable space-efficient designs for high-resolution blood flow monitoring.

Main Methods:

Development of a 64x64 pixel CMOS imaging array.

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Blood Flow Imaging with Ultrafast Doppler

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Integration of analog and digital on-chip processing electronics.

Testing with simulated blood flow responses and a blood flow occlusion test.

Main Results:

Successful demonstration of a fully integrated CMOS imaging array for laser Doppler blood flow imaging.
On-chip processing tailored to blood flow signals, overcoming data bottlenecks.
Validation of the sensor's capability through simulated and real-world blood flow tests.

Conclusions:

The integrated CMOS sensor represents a significant advancement for laser Doppler blood flow imaging.
On-chip processing enhances efficiency and enables compact designs.
This technology holds promise for improved non-invasive blood flow monitoring applications.