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Published on: July 5, 2016
Acousto-optical coherence tomography with a digital holographic detection scheme
Emilie Benoit a la Guillaume1, Salma Farahi, Emmanuel Bossy
1Institut Langevin, ESPCI ParisTech, CNRS UMR 7587, INSERM U979, Université Paris VI‐Pierre et Marie Curie, Paris, France. emilie.benoit@espci.fr
Acousto-optical coherence tomography combined with digital holography achieves millimeter resolution imaging in scattering media. This study optimizes phase modulation for better signal amplitude, contrast, and inclusion size in phantom imaging.
Area of Science:
- Biomedical Optics
- Acousto-Optics
- Holography
Background:
- Imaging thick scattering media remains challenging.
- Acousto-optical coherence tomography (AOCT) offers potential for deep tissue imaging.
- Combining AOCT with digital holography can enhance resolution and signal quality.
Purpose of the Study:
- To investigate the combination of AOCT with heterodyne off-axis digital holography.
- To obtain high-resolution 2D images of absorbing objects in scattering phantoms.
- To analyze the effect of phase modulation on AOCT signal characteristics.
Main Methods:
- Utilized random phase jumps in ultrasound and light for AOCT.
- Integrated heterodyne off-axis digital holography.
- Imaged absorbing objects embedded within scattering phantoms.
- Studied the impact of phase modulation parameters.
Main Results:
- Achieved millimeter resolution imaging in thick scattering media.
- Obtained 2D images with good signal-to-noise ratio.
- Characterized the influence of phase modulation on signal amplitude, contrast, and apparent inclusion size.
Conclusions:
- The combined AOCT and digital holography technique enables effective imaging of embedded absorbers in scattering environments.
- Phase modulation is a critical factor influencing image quality and quantitative measurements.
- This approach shows promise for advanced biomedical imaging applications.
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