A high-throughput approach for measuring temporal changes in the interactome

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Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling
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Label-Free Immunoprecipitation Mass Spectrometry Workflow for Large-scale Nuclear Interactome Profiling

Published on: November 17, 2019

Anders R Kristensen1, Joerg Gsponer, Leonard J Foster

  • 1Department of Biochemistry & Molecular Biology, University of British Columbia, Vancouver, British Columbia, Canada.

Nature Methods
|August 7, 2012
PubMed

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Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...