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Related Concept Videos

Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Regulation of Hormone Secretion01:19

Regulation of Hormone Secretion

Regulation of hormone secretion is a finely tuned orchestration driven by various types of stimuli, encompassing neural, humoral, and hormonal signals. Environmental cues instigate neural stimuli, where action potentials traverse nerve fibers to reach their designated targets. An illustrative scenario is the body's response to stress, wherein the sympathetic nervous system releases epinephrine from the adrenal glands, inducing the well-known 'fight or flight' reaction.
Humoral stimuli,...
Hormonal Control of the Ovarian Cycle01:30

Hormonal Control of the Ovarian Cycle

The ovarian cycle is meticulously regulated by the hypothalamic-pituitary-gonadal axis. This cycle orchestrates the release of a mature oocyte, essential for reproduction.
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Testosterone: Functions and Regulation01:26

Testosterone: Functions and Regulation

The intricate hormonal interplay essential for male reproductive health begins with the release of gonadotropin-releasing hormone (GnRH) by the hypothalamus. This hormone prompts the pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). LH targets the Leydig cells in the testes, stimulating them to produce and release testosterone. In concert with testosterone, FSH acts on the Sertoli cells within the seminiferous tubules to facilitate the release of...
Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH release.
Hormones of the Pituitary Gland01:27

Hormones of the Pituitary Gland

The small, pea-sized pituitary gland is located at the base of the brain. It is crucial in regulating various bodily functions, from growth to reproduction. The gland is divided into the anterior lobe and the posterior lobe. The secretory cell clusters in the pars distalis of the anterior pituitary lobe are controlled by hypothalamic regulators and synthesize six primary hormones.
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...

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Updated: May 19, 2026

Unraveling the Role of Discrete Areas of the Rat Brain in the Regulation of Ovulation through Reversible Inactivation by Tetrodotoxin Microinjections
11:04

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Published on: September 3, 2020

The hormonal control of ejaculation.

Giovanni Corona1, Emmanuele A Jannini, Linda Vignozzi

  • 1Endocrinology Unit, Medical Department, Azienda Usl Bologna Maggiore-Bellaria Hospital, Largo Nigrisoli 2, 40133 Bologna, Italy.

Nature Reviews. Urology
|August 8, 2012
PubMed
Summary
This summary is machine-generated.

Hormones significantly influence male reproduction and ejaculation. Understanding these endocrine mechanisms, including oxytocin and thyroid hormones, may lead to effective treatments for ejaculatory disorders.

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Last Updated: May 19, 2026

Unraveling the Role of Discrete Areas of the Rat Brain in the Regulation of Ovulation through Reversible Inactivation by Tetrodotoxin Microinjections
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Published on: September 3, 2020

Treatment of Ejaculatory Duct Obstruction by Seminal Vesiculoscopy Assisted Flow Modification
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Area of Science:

  • Endocrinology
  • Reproductive Medicine
  • Neuroscience

Background:

  • Hormones are crucial for male reproductive functions, including sexual drive and sperm production.
  • While the role of hormones in ejaculation is suggested by animal and human studies, precise mechanisms remain unclear.
  • Oxytocin, thyroid hormones, glucocorticoids, oestrogens, and testosterone are implicated in regulating the ejaculatory process.

Purpose of the Study:

  • To review the current understanding of hormonal regulation of the male ejaculatory process.
  • To explore the involvement of various hormones, including oxytocin, thyroid hormones, and sex steroids, in ejaculation.
  • To discuss the potential therapeutic implications of endocrine modulation for ejaculatory disorders.

Main Methods:

  • Literature review of animal models and human clinical studies.
  • Analysis of evidence regarding the roles of oxytocin, thyroid hormones, glucocorticoids, oestrogens, and testosterone.
  • Synthesis of findings on peripheral, central, and spinal mechanisms of hormonal control.

Main Results:

  • Oxytocin plays a significant role in orgasm and ejaculation through multiple pathways.
  • Thyroid dysfunction is associated with delayed (hypothyroidism) and premature ejaculation (hyperthyroidism).
  • Testosterone influences central and peripheral aspects of ejaculation, while oestrogens affect epididymal motility.

Conclusions:

  • Hormonal regulation is integral to the male ejaculatory reflex.
  • Endocrine therapies targeting identified hormonal imbalances may offer effective treatments for sexual dysfunction.
  • Treating thyroid diseases can improve ejaculatory difficulties, highlighting the potential of endocrine interventions.