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[Chlamydia trachomatis infection in women]
V Jerant-Patić1, J Ziramov, V Vujkov
1Institut za zdravstvenu zastitu, N. Sad.
Medicinski Pregled
|January 1, 1990
Summary
Chlamydia trachomatis infections are common in women, particularly those with sterility or cervical changes. Diagnostic testing, like indirect immunofluorescent test and ELISA, is crucial for identifying these infections.
Area of Science:
- Gynecologic infectious diseases
- Immunology
- Microbiology
Context:
- Chlamydia trachomatis is a significant cause of gynecologic infections.
- Accurate diagnostic methods are essential for timely treatment and management.
- Previous studies have highlighted the prevalence of Chlamydia trachomatis in various patient populations.
Purpose:
- To evaluate the prevalence of Chlamydia trachomatis infection in a cohort of 288 women.
- To assess the diagnostic performance of indirect immunofluorescent test (IIF), ELISA, and complement-fixation tests.
- To determine the association between Chlamydia trachomatis infection and clinical conditions such as sterility, cervical changes, and pathological pregnancies.
Summary:
- Chlamydia trachomatis infection was detected in 29.51% of women using IIF and ELISA tests.
- Infections were more prevalent in women with sterility (compared to the general cohort) and cervical changes (endocervicitis, erythroplasia).
- A high prevalence (40.91%) was observed in women with a history of pathological pregnancies/births, and humoral immune response was detected in 70.59% of cases.
- The combination of IIF and ELISA demonstrated superior diagnostic accuracy.
Impact:
- Highlights the high prevalence of Chlamydia trachomatis in women, underscoring the need for effective screening.
- Provides insights into the association between Chlamydia trachomatis and adverse gynecologic and obstetric outcomes.
- Recommends the combined use of IIF and ELISA for improved Chlamydia trachomatis diagnosis in clinical settings.