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Updated: May 19, 2026
09:07
An Orthotopic Model of Murine Bladder Cancer
Published on: February 6, 2011
[A case of micropapillary bladder carcinoma]
Eiri Matsumura1, Asuka Ashikari, Shinsuke Tasaki
1The Department of Urology, Graduate School and Faculty of Medicine, University of the Ryukyus.
Hinyokika Kiyo. Acta Urologica Japonica
|August 10, 2012
Summary
A rare micropapillary bladder carcinoma case highlights its aggressive nature. Successful treatment involved radical cystectomy and chemotherapy, leading to a 28-month recurrence-free survival.
Area of Science:
- Uro-oncology
- Pathology
- Surgical Oncology
Background:
- Urothelial carcinoma is the most common bladder cancer.
- Micropapillary variant of urothelial carcinoma is a rare subtype with aggressive behavior.
- Early diagnosis and appropriate management are crucial for patient outcomes.
Observation:
- A 45-year-old male presented with hematuria, diagnosed with bladder cancer.
- Initial transurethral resection revealed poorly differentiated adenocarcinoma invading the muscle layer.
- Pathological diagnosis confirmed the rare micropapillary variant of urothelial carcinoma.
Findings:
- Radical cystectomy and pelvic lymph node dissection were performed.
- Adjuvant chemotherapy with gemcitabine and cisplatin was administered in three courses.
- The patient achieved a 28-month recurrence-free and metastasis-free survival post-treatment.
Implications:
- This case underscores the importance of accurate pathological diagnosis for rare variants.
- Aggressive surgical and chemotherapeutic approaches may be effective for micropapillary bladder carcinoma.
- Long-term surveillance is essential for patients treated for this aggressive cancer variant.
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