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High-performance liquid chromatographic determination of alpha-tocopherol in inclusion complexes with cyclodextrins
Teresa Gierlach-Hładoń1, Kinga Lange
1Department of Inorganic and Analytical Chemistry, Karol Marcinkowski University of Medical Sciences, Grunwaldzka 6, 60-780 Poznań, Poland.
Acta Poloniae Pharmaceutica
|August 11, 2012
Abstract:
A new high performance liquid chromatography (HPLC)-based method is proposed for the determination of vitamin E, free and in inclusion complexes with natural beta-cyclodextrin and its 2-hydroxy derivative. The method has been validated on the basis of the following parameters: specificity, selectivity, linearity, precision, range and recovery.