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Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
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Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
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Appendicitis01:19

Appendicitis

Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Abnormal Proliferation02:23

Abnormal Proliferation

Under normal conditions, most adult cells remain in a non-proliferative state unless stimulated by internal or external factors to replace lost cells. Abnormal cell proliferation is a condition in which the cell's growth exceeds and is uncoordinated with normal cells. In such situations, cell division persists in the same excessive manner even after cessation of the stimuli, leading to persistent tumors. The tumor arises from the damaged cells that replicate to pass the damage to the daughter...
Plasmodesmata02:32

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The organs in a multicellular organism’s body are made up of tissues formed by cells. To work together cohesively, cells must communicate. One way that cells communicate is through direct contact with other cells. The points of contact that connect adjacent cells are called intercellular junctions.

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Related Experiment Videos

Plasmacytoma masquerading as an abscess.

Kanwar Deep Singh Nanda1, Deepak Bhargava, Bhudev Sharma

  • 1Department of Oral and Maxillofacial Pathology, Sri Gobind Tricentenary Dental and Medical College and Hospital, Gurgaon, Haryana, India. kdsnanda@gmail.com

Journal of Investigative and Clinical Dentistry
|August 14, 2012
PubMed
Summary
This summary is machine-generated.

Extramedullary plasmacytoma, a rare soft tissue tumor, can occur in the head and neck. This case highlights an extremely rare instance of maxillary plasmacytoma in a 70-year-old male.

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Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Plasma cell neoplasia encompasses multiple myeloma and plasmacytomas.
  • Extramedullary plasmacytoma (EMP) involves plasma cell proliferation in soft tissues.
  • Head and neck EMPs are rare, accounting for 0.4% of malignancies in this region.

Observation:

  • A 70-year-old male presented with facial swelling mimicking an abscess.
  • The swelling was located in the right middle third of the face.
  • Diagnostic workup revealed extramedullary plasmacytoma of the maxilla.

Findings:

  • Maxillary plasmacytoma is an exceptionally rare presentation of head and neck EMP.
  • The case involved detailed clinical, radiographic, histological, and immunohistochemical analysis.
  • Immunohistochemistry confirmed the neoplastic plasma cell origin.

Implications:

  • This case underscores the importance of considering rare diagnoses in head and neck swellings.
  • Accurate diagnosis of EMP requires a combination of imaging and pathological evaluation.
  • Understanding the features of rare tumors like maxillary EMP aids in appropriate patient management.