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Production of consistent pain by intermittent infusion of sterile 5% hypertonic saline, followed by decrease of pain
Blaine C Long1, Kenneth L Knight, Ty Hopkins
1Dept of Health and Human Performance, Oklahoma State University, Stillwater, OK, USA.
Journal of Sport Rehabilitation
|August 17, 2012
Summary
This study developed an experimental anterior knee pain model using hypertonic saline infusion. Cryotherapy effectively reduced induced pain for 16 minutes, offering a potential therapeutic strategy.
Area of Science:
- Orthopedics
- Pain Management
- Therapeutic Modalities
Background:
- Experimental pain models are crucial for studying post-injury pain.
- Cryotherapy (cryo) is used to minimize pain, but its effectiveness requires further investigation.
Purpose of the Study:
- To establish a reliable experimental pain model for the anterior knee.
- To evaluate the efficacy of cryotherapy in alleviating induced anterior knee pain.
Main Methods:
- A controlled laboratory study involving 30 healthy male subjects.
- Induced anterior knee pain using intermittent hypertonic saline infusion.
- Measured perceived pain and surface temperature, comparing cryotherapy and sham interventions.
Main Results:
- The hypertonic saline infusion successfully created an experimental pain model.
- Cryotherapy significantly reduced induced anterior knee pain for up to 16 minutes.
- No significant changes in surface temperature were observed in the sham group.
Conclusions:
- Intermittent hypertonic saline infusion is a viable method for creating a controlled experimental anterior knee pain model.
- Cryotherapy demonstrates effectiveness in reducing experimentally induced anterior knee pain, suggesting its potential therapeutic application.
