Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[The visual evoked potentials in ischemic optic neuropathy].

D Xin1, L Wu, D Wu

  • 1Department of Ophthalmology, Guangdong Provincial People's Hospital, Guangzhou, China.

Yan Ke Xue Bao = Eye Science
|December 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The effect of carotenoids on the expression of cell surface adhesion molecules and binding of monocytes to human aortic endothelial cells.

Atherosclerosis·2000
Same author

Primary structure and functional characterization of a soluble, alternatively spliced form of B7-1.

Journal of immunology (Baltimore, Md. : 1950)·2000
Same author

Regional analysis of divorce in China since 1980.

Demography·2000
Same author

Role of Raf-1 conserved region 2 in regulation of Ras-dependent Raf-1 activation.

Biochemical and biophysical research communications·2000
Same author

[Loss of heterozygosity and microsatellite instability in laryngeal carcinoma near p16 gene].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics·2000
Same author

Acute effects of growth hormone in alcohol-fed rats.

Alcohol and alcoholism (Oxford, Oxfordshire)·2000
Same journal

[anastomosis lacrimal sac conjunctival sac in severe laceration of lacrimal canaliculus].

Yan ke xue bao = Eye science·2010
Same journal

[Ultrastructural changes of the trabecular meshwork in glucocorticoid induced glaucoma].

Yan ke xue bao = Eye science·2010
Same journal

[An in vivo study of basic fibroblast growth factor on activation and proliferation of retinal progenitor cell in RCS rats].

Yan ke xue bao = Eye science·2010
Same journal

[Inhibitory effect of diclofenac sodium on the proliferation of rabbit corneal epithelial cells in vitro].

Yan ke xue bao = Eye science·2010
Same journal

[The photopic electroretinogram in normal adult sd rat].

Yan ke xue bao = Eye science·2010
Same journal

[An improved method of culturing human umbilical vein endothelial cells and its characterization].

Yan ke xue bao = Eye science·2010
See all related articles

Ischemic optic neuropathy (ION) significantly damages visual function, primarily causing decreased VEP amplitude and increased latency. Contrast sensitivity and visual field defects are also common, correlating with VEP abnormalities.

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Optic Nerve Disorders

Context:

  • Ischemic optic neuropathy (ION) is a leading cause of sudden, painless vision loss.
  • Understanding the electrophysiological and psychophysical changes in ION is crucial for diagnosis and management.

Purpose:

  • To analyze the clinical visual evoked potential (VEP) in ischemic optic neuropathy (ION) using pattern-reversal stimulation.
  • To compare VEP findings with visual field (VF) and contrast sensitivity (CS) examinations at various spatial frequencies.
  • To investigate the correlation between VEP parameters and other visual function tests in ION patients.

Summary:

  • VEP analysis in 27 ION cases revealed decreased amplitude (81.3% abnormal) as the dominant feature, with a slight latency increase (83.5% abnormal).

Related Experiment Videos

  • Reduced contrast sensitivity (CS) was prominent at middle and high spatial frequencies.
  • A significant correlation was found between VEP amplitude and CS. Visual field defects, including arcuate scotoma, were common, linked to central visual field impairment.

    • Impact:

    • Abnormal VEP findings are strongly associated with visual dysfunction in ION.
    • This study highlights the utility of VEP, VF, and CS in assessing the extent of visual impairment in ION.
    • Longitudinal VEP follow-up indicated a progressive decline in VEP amplitude, suggesting ongoing visual function damage in ION.