Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Heart Failure VI: Adjunct Therapies

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

Cardiomyopathy V: Interprofessional Care

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

Mechanical Ventilation II: Invasive Ventilation

Mechanical Ventilation II: Invasive Ventilation

Ventilators are essential medical equipment used to aid patients with respiratory difficulties. Their primary function is to assist or replace spontaneous breathing by providing mechanical ventilation. There are two general classes of mechanical ventilators: negative-pressure and positive-pressure ventilators.
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...

Mechanical Ventilation III: Noninvasive Ventilation

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)

Ventilatory Modes

Ventilatory Modes

Mechanical ventilators are life-saving devices that support or replace spontaneous breathing. They deliver breaths to patients through varying methods known as ventilator modes. Understanding these modes is critical for healthcare providers managing patients with respiratory failure.
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

Heart Failure Drugs: Inotropic Agents

Heart Failure Drugs: Inotropic Agents

Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Effect of large volume paracentesis performed just prior to transjugular intrahepatic portosystemic shunt on the anesthetic management during the procedure.

Journal of anaesthesiology, clinical pharmacology·2021

Same author

Transesophageal Echocardiographic Guidance in the Implantation of a Watchman Left Atrial Appendage Closure Device.

A&A practice·2020

Same author

Successful management of hypothermic cardiopulmonary bypass in a malignant hyperthermia susceptible patient.

Annals of cardiac anaesthesia·2020

Same author

Use of Intracardiac Echocardiography to Differentiate Post-Transcatheter Aortic Valve Replacement Valve Insufficiency Masquerading as Paravalvular Leak.

CASE (Philadelphia, Pa.)·2020

Same author

Perioperative takotsubo cardiomyopathy: Implications for anesthesiologist.

Annals of cardiac anaesthesia·2019

Same author

My Personal Tryst with Ketamine Anesthesia.

Anesthesiology·2019

Search research articles

Related Experiment Video

Updated: May 19, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Newer-generation ventricular assist devices.

Shvetank Agarwal¹, Kane M High

¹Department of Anesthesiology, Penn State Hershey, PO Box 850, Hershey, PA 17033, USA. sagarwal1@hmc.psu.edu

Best Practice & Research. Clinical Anaesthesiology

|August 23, 2012

Summary

Modern rotary ventricular assist devices offer improved reliability and smaller size compared to older pulsatile pumps. These advanced pumps are increasingly approved for bridge to transplant and destination therapy, enhancing patient care.

More Related Videos

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

Related Experiment Videos

Last Updated: May 19, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart

Published on: May 11, 2018

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock

Published on: August 16, 2021

Area of Science:

Cardiovascular Engineering
Medical Devices
Biomedical Engineering

Background:

Ventricular assist devices (VADs) have evolved significantly from early pulsatile pumps.
Current VAD technology focuses on rotary pumps, including centrifugal and axial flow designs.

Purpose of the Study:

To review the latest generation of rotary ventricular assist devices.
To examine design features and regulatory approval status (FDA and CE mark) of current VADs.

Main Methods:

Review of current and developing rotary pump technologies.
Analysis of device design characteristics.
Examination of regulatory approval status for bridge to transplant (BTT) and destination therapy (DT).

Main Results:

Rotary pumps demonstrate superior duty life and reliability over pulsatile pumps.
Rotary pumps are smaller, enabling less invasive implantation and smaller drivelines.
Several rotary VADs are approved as BTT, with some undergoing trials for DT in Europe and the US.

Conclusions:

The current generation of rotary VADs represents a significant advancement in mechanical circulatory support.
These devices offer improved patient outcomes through enhanced reliability and less invasive implantation.
Ongoing trials for destination therapy indicate broader future applications for these VADs.