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Updated: May 19, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
[Insular psammomatous meningioma presenting intractable complex partial seizures]
Hirochika Imoto1, Masami Fujii, Yuichi Maruta
1Department of Neurosurgery, Yamaguchi University School of Medicine, Japan.
Abstract:
We describe a 30-year-old female with intractable symptomatic epilepsy caused by an insular calcified mass, which was histologically proved as psammomatous meningioma. Seizures were described as consciousness impairment, motionless stare and automatism. After total removal of the tumor with a neuronavigation system and motor evoked potential (MEP) monitoring, seizures completely disappeared without neurological deficit. We emphasize that insular meningioma presents complex partial seizures which mimic medial temporal lobe epilepsy and seizures are controlled by total resection of the tumor.
Insights
A calcified insular psammomatous meningioma caused intractable epilepsy in a 30-year-old female. Surgical removal of the tumor led to complete seizure resolution without neurological deficits, highlighting effective treatment.
Area of Science:
- Neurosurgery
- Neurology
- Pathology
Background:
- Epilepsy is a neurological disorder characterized by recurrent seizures.
- Insular brain lesions can present with complex partial seizures mimicking other epilepsy types.
- Meningiomas are tumors arising from the meninges, the membranes surrounding the brain and spinal cord.
Observation:
- A 30-year-old female presented with intractable symptomatic epilepsy.
- The epilepsy was caused by a calcified mass in the insular region of the brain.
- Histological examination confirmed the mass as a psammomatous meningioma.
Findings:
- The patient experienced seizures characterized by impaired consciousness, motionless stare, and automatism.
- Surgical resection of the insular meningioma was performed using neuronavigation and motor evoked potential (MEP) monitoring.
- Complete removal of the tumor resulted in the complete cessation of seizures.
- No neurological deficits were observed post-operatively.
Implications:
- Insular meningiomas can manifest as complex partial seizures that closely resemble medial temporal lobe epilepsy.
- Total surgical resection is an effective treatment for epilepsy caused by insular meningiomas.
- This case underscores the importance of considering rare intracranial lesions in the differential diagnosis of refractory epilepsy.
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