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Related Experiment Video

Updated: May 19, 2026

Symptom Assessment of Patients with Allergic Rhinitis Using an Allergen Exposure Chamber

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Published on: March 3, 2023

Allergen-specific immunotherapy for atopic eczema: updated.

¹Department of Dermatology and Allergy Biederstein, Technische Universität München, ZAUM - Center for Allergy and Environment, Munich, Germany. ulf.darsow@lrz.tum.de

Current Opinion in Allergy and Clinical Immunology

|August 25, 2012

Summary

Allergen-specific immunotherapy (ASIT) shows promise for treating atopic eczema in patients with specific allergies. This therapy can improve eczema symptoms and is generally well-tolerated, with the atopy patch test potentially identifying suitable candidates.

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Area of Science:

Dermatology
Allergology
Immunotherapy

Background:

Aeroallergens trigger respiratory allergies and atopic eczema in some individuals.
The efficacy of allergen-specific immunotherapy (ASIT) for atopic eczema is debated due to limited controlled studies.

Purpose of the Study:

To review theoretical aspects and recent clinical trial results of ASIT in atopic eczema.
To assess the potential of ASIT as a curative therapy for atopic eczema.

Main Methods:

Review of theoretical aspects of ASIT.
Analysis of recent clinical trial data on ASIT for atopic eczema.

Main Results:

ASIT may improve atopic eczema in patients with Type I sensitizations.
Studies indicate ASIT efficacy for house dust mite, birch, and grass pollen allergies in eczema patients.
Positive ASIT outcomes were observed in specific patient subgroups, with good tolerability.

Conclusions:

Atopic eczema patients with relevant allergies may benefit from ASIT as an additional treatment.
Potential side effects of ASIT may have been overestimated.
The atopy patch test could help identify patient subgroups for successful ASIT.