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Updated: May 19, 2026

Optimized Minimally Invasive Transscleral Subretinal Injection Technique in Mouse
Published on: July 25, 2025
Minimally invasive external mini-glaucoma shunt implantation without conjunctival dissection
Richard S Hoffman1, Alan S Crandall, David A Crandall
1*Drs Fine Hoffman & Packer LLC, Eugene, OR †John A. Moran Eye Center, University of Utah, Salt Lake City, UT ‡Henry Ford Health System, Detroit, MI.
Abstract:
The current method for implantation of the Ex-PRESS Glaucoma Filtration Device requires a conjunctival peritomy and shunt insertion under the guarded protection of a scleral flap. This technique requires suture closure of the flap and conjunctiva. A new minimally invasive technique for Ex-PRESS shunt implantation allows for insertion through a scleral tunnel originating from a grooved clear corneal incision. This new method avoids the need for conjunctival dissection and closure and offers the advantages of eliminating conjunctival wound leaks while maintaining the protection of a partial thickness scleral covering. This new technique may offer a faster safer means for shunt implantation with the potential for less conjunctival scarring.
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