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Published on: April 2, 2021
Factors given by birth and oxygen therapy in relation to development of retinopathy of prematurity
Maja Olujić1, Ana Oros, Alekandra Bregun Doronjski
1Klinicki centar Vojvodine Novi Sad, Medicinski fakultet Novi Sad.
Insights
Premature birth is the primary risk factor for retinopathy of prematurity, a leading cause of childhood blindness. Gestational age is the most significant birth-related factor influencing its development.
Area of Science:
- Ophthalmology
- Neonatology
- Pediatrics
Background:
- Retinopathy of prematurity (ROP) is a major cause of childhood blindness globally.
- ROP affects the retina's blood vessels in premature infants.
- Birth factors and health status influence ROP development.
Purpose of the Study:
- Investigate birth-related factors and oxygen use in ROP development.
- Determine the significance of gestational age and oxygen therapy on ROP.
- Identify key risk factors for premature retinopathy.
Main Methods:
- Prospective study conducted over two years.
- Examined parameters: weight, gestational age, duration of oxygenotherapy, and mechanical ventilation.
- Included eye fundus findings for analysis.
Main Results:
- Gestational age identified as the most critical birth factor for ROP development.
- Strong correlation between prematurity and ROP risk.
- Oxygen therapy parameters also considered in relation to ROP.
Conclusions:
- Premature birth is the paramount risk factor for retinopathy of prematurity.
- Gestational age is a key determinant in ROP.
- Understanding these factors is crucial for prevention and management.
Introduction:
Retinopathy of prematurity is a disease of the eye which affects the blood vessels of the retina and represents the most important cause of blindness and low vision in children worldwide. There are many risk factors given by birth and parameters of general health status that may influence this disease. The aim of this study was to investigate the significance of the factors given by birth and use of oxygen in relation to the development of premature retinopathy.
Material And Methods:
A two-year-long prospective study was done at the Institute for Child and Youth Health Care of Vojvodina. In this study the following parameters were examined: weight, gestational age as a factor given by birth and parameters of oxygenotherapy--the number of days on oxygenotherapy and the number of days of mechanical ventilation. The findings on the eye fundus were also taken into consideration.
Results:
The test results suggest that the gestational age is the most important factor given by birth which determines the possibility of development of premature retinopathy.
Conclusion:
In fact, the most important risk factor for the development of premature retinopathy is premature birth.
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